Procurement comparison · Updated 2026-06-28
Grafix vs. Kindr
Grafix Core / Grafix PRIME (cryopreserved placental) · Osiris Therapeutics (Smith+Nephew) · Q4133
Kindr Health's amniotic allograft line is offered in both ambient-stable lyophilized and cryopreserved formats with multi-source supply continuity. The comparison below focuses strictly on supply chain, storage, and billing attributes — not clinical efficacy.
Supply chain & storage
- Storage
- Grafix: –80 °C cryopreservation required. Kindr cryopreserved: –80 °C; lyophilized alternative is ambient.
- Shelf life
- Grafix: 2 years at –80 °C. Kindr cryopreserved: 2 years at –80 °C; lyophilized: 3–5 years ambient.
- Cold chain risk
- Grafix has high cold chain dependency — break in chain renders product unusable. Sites with intermittent use or unreliable freezer infrastructure typically see materially higher waste vs. lyophilized alternatives.
- Sizes
- Grafix offers smaller standard sizes (typically 1.5–5 cm²). Kindr offers comparable sizes in both formats.
Billing & reimbursement
- Q-code
- Grafix: Q4133.
- Payment basis
- ASP+6% in physician office; OPPS APC packaged in HOPD.
- LCD notes
- Cryopreserved placental products are covered under most MAC LCDs for chronic DFU and VLU.
Procurement takeaway
Grafix vs. Kindr is largely a cold-chain question: high-volume hospital wound centers with reliable –80 °C infrastructure may run cryopreserved without waste exposure; multi-site, ambulatory, and SNF operations almost always see lower TCO with a lyophilized alternative.
Run side-by-side TCO →Other comparisons
Comparison data drawn from publicly available manufacturer IFUs, product labels, and CMS HCPCS files as of 2026-06-28. Trademarks belong to their respective owners. No clinical superiority is claimed or implied. Verify all data against current manufacturer documentation before procurement decisions.